Conditioned Media from Adipose-Tissue-Derived Mesenchymal Stem Cells Downregulate Degradative Mediators Induced by Interleukin-1β in Osteoarthritic Chondrocytes
Figure 7
Effects of CM on NF-B activation in OA chondrocytes. Cells were stimulated with IL-1 for 1 h and p65-NF-B binding to DNA was determined by ELISA in nuclear fractions. Data are expressed as mean ± S.E.M. of independent cultures with chondrocytes from 3 different donors. AU: arbitrary units. + with respect to nonstimulated cells; * with respect to IL-1.
