PD-L1 Blockade Attenuated Sepsis-Induced Liver Injury in a Mouse Cecal Ligation and Puncture Model
Anti-PD-L1 antibody altered mRNA expression of IL-6, IL-10, and TNF-α in the liver of septic mice. Mice were administered anti-PD-L1 antibody (50 μg, i.p.). Liver specimens were sampled 24 hours after surgery. versus Sham, versus CLP, (IL-6), (IL-10), and (TNF-α) versus CLP. Bars represent the mean ± SD of eight mice for each group.
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