Research Article

Intricacies for Posttranslational Tumor-Targeted Cytokine Gene Therapy

Figure 4

Tumor-targeting PF4 gene therapy with the VNTANST sequence does not improve anticancer efficacy. Black arrows represent treatments. # represents compared to all other groups. (a) Only wtPF4 was capable of inhibiting primary tumor growth, but both wtPF4 and ttPF4 equally inhibited the development of lung metastases (b). Black arrows represent treatments. # represents compared to all other groups.
378971.fig.004a
(a)
378971.fig.004b
(b)