Heat Shock Proteins 60 and 70 Specific Proinflammatory and Cytotoxic Response of CD4⁺CD28^null Cells in Chronic Kidney Disease

Figure 4

Relative mRNA expression of INF-𝛾, perforin, and granzyme B in CD4⁺CD28^null cells in healthy subjects. No antigenic response was observed in cells stimulated with HSP60 (5 ng/mL) and HSP70 (5 ng/mL), whereas PHA (10 𝜇g/mL) (positive control) showed increased expression of mRNA.