Fractalkine (CX3CL1) and Its Receptor CX3CR1 May Contribute to Increased Angiogenesis in Diabetic Placenta
Table 1
Clinical characteristics of the two studied groups: diabetes class C after White (group I) versus normal-course pregnancies (group II).
Parameter
Group I (diabetes class C)
Group II (normal controls)
Number of patients/placentae/newborns ()
11/11/11
11/11/11
Age of the patients in full years (range; mean; median)
26–33; 29; 28
22–33; 27; 26
Parity
0
0
Gestational age in days (range; mean; median)
242–258; 250; 252
249–257; 253; 255
Method of delivery
Cesarean section
Cesarean section
1st minute Apgar’s score (range; mean)
8–10; 9.3
9-10; 9.7
Blood pressure during pregnancy
All records within normal rangea
All records within normal rangea
Proteinuria during pregnancy
Not presentb
Not present
Liver blood tests (aminotransferases enzymes AST and ALT levels)
Within normal rangec
Within normal rangec
Smoking during pregnancy
1 declared >5 cigarettes per day
2 declared >5 cigarettes per day
Body Mass Index <21 or >35
None
None
Other identified risk factors
None
None
Birth weight in grams (range; mean; median)
2995–3590; 3386; 3277
3056–3440; 3307; 3320
Newborns gender (M—male; F—female)
4M + 7F
6M + 5F
Weight of placenta in grams (range; mean, median)
425–616; 571; 563
482–626; 554; 539
The normal range of the blood pressure was defined as systolic pressure between 100 and 140 mm Hg and diastolic pressure between 60 and 90 mm Hg.
bMicroalbuminuria (urinary albumin excretion in the range of 30–300 mg/24 h) not present.
cThe normal range of values for AST is from 5 to 40 units per liter of serum, and the normal range of values for ALT is from 7 to 56 units per liter of serum.
