Rheumatoid Arthritis Impacts on the Independent Relationships between Circulating Adiponectin Concentrations and Cardiovascular Metabolic Risk
Table 1
Baseline characteristics in subjects with and without rheumatoid arthritis.
Characteristic
Rheumatoid arthritis
Present ()
Absent ()
Demographics
Age
55.8 (10.2)
56.5 (10.9)
0.6
Female (%)
89.1
86.1
0.4
Lifestyle factors
Alcohol use (%)
0.8
17.7
0.006
Units per week, *
0.01 (0.07)
0.27 (1.09)
0.001
Exercise (%)
40.3
43.0
0.6
Hours per week,
0.01 (1.00)
1.7 (2.4)
0.0001
Smoking (%)
3.4
8.2
0.1
Cigarettes per day
0.05 (0.37)
0.15 (0.69)
0.06
Anthropometric measures
BMI, kg/m2
29.3 (6.6)
33.7 (8.0)
<0.0001
Waist circumference, cm
93.3 (13.4)
97.5 (15.1)
0.02
Waist-hip ratio*
0.86 (0.12)
0.85 (0.10)
0.4
Cardiovascular drugs
Antihypertensive agents
Use (%)
54.6
40.0
0.02
Number
1.0 (1.1)
0.5 (0.7)
<0.0001
Diuretic (%)
39.5
38.6
0.9
ACEI (%)
39.5
7.0
<0.0001
CCB (%)
17.7
5.1
0.002
BB (%)
3.4
0
—
ARB (%)
0.8
0
—
Glucose lowering agents
Oral glucose lowering agent (%)
13.5
10.1
0.4
Insulin (%)
0.8
2.5
0.6
Statin (%)
19.4
0
—
NSAID (%)
6.7
4.4
0.3
Systemic inflammation
CRP (mg/L)*
7.0 (3.1)
6.7 (3.1)
0.7
Results are expressed as mean (SD) or proportions/percentages. : number; BMI: body mass index; ACEI: angiotensin converting enzyme inhibitor; CCB: calcium channel blocker, BB: beta blocker, ARB: angiotensin receptor blocker; NSAID: nonsteroidal anti-inflammatory agent; CRP: C-reactive protein.
*Nonnormally distributed variables for which geometric mean (SD) is given. †Denotes active RA.
