Rheumatoid Arthritis Impacts on the Independent Relationships between Circulating Adiponectin Concentrations and Cardiovascular Metabolic Risk

Table 2

Metabolic cardiovascular risk factor profiles and carotid atherosclerosis in subjects with and without rheumatoid arthritis.

Characteristic	Rheumatoid arthritis
	Present (𝑛=119)	Absent (𝑛=158)
Categorical variables			OR (95% CI)*
Hypertension (%)	74.0	65.2	1.47 (0.87 to 2.48)
Total C-HDL C ratio > 4	21.7	33.8	0.53 (0.29 to 0.96)
Diabetes (%)	16.0	12.0	1.46 (0.74 to 2.88)
Continuous variables			𝑃^∗
Blood pressure values
SBP, mmHg	140 (25)	137 (22)	0.3
DBP, mmHg	86 (15)	87 (13)	0.5
MBP, mmHg	104 (17)	104 (15)	0.9
Lipid values
Total C, mmol/L	4.7 (0.9)	5.1 (1.2)	0.02
HDL C^†, mmol/L	1.48 (1.34)	1.39 (1.32)	0.04
Total C-HDL C ratio	3.2 (1.1)	3.7 (1.3)	0.0002
LDL C, mmol/L	2.6 (0.8)	3.0 (1.0)	0.003
Non HDL C, mmol/L	3.1 (0.9)	3.6 (1.2)	0.0001
Trig^†, mmol/L	1.1 (1.7)	1.2 (1.6)	0.03
Trig-HDL C ratio^†	0.73 (2.05)	0.87 (1.85)	0.01
Cigarettes smoked per day^†, 𝑛	0.05 (0.37)	0.15 (0.68)	0.08
Glucose^†, mmol/L	5.3 (1.4)	5.5 (1.4)	0.1
Carotid atherosclerosis
cIMT, mm	0.694 (0.098)	0.704 (0.121)	0.5

Results are expressed in mean (SD) or proportions/percentages. Significant associations are shown in bold. C: cholesterol; HDL: high density lipoprotein; Trig: triglycerides; SBP: systolic blood pressure; DBP: diastolic blood pressure; MBP: mean blood pressure; LDL: low density lipoprotein; 𝑛: number; CHD: coronary heart disease; CVD: cardiovascular disease; cIMT: carotid intima-media thickness.
*Adjusted for age and sex with additional adjustment for antihypertensive, statin, and glucose lowering therapy in models that included blood pressure, lipid, and glucose variables, respectively.
^†Nonnormally distributed variables for which geometric means (SD) are given.