Review Article

Alteration of Energy Substrates and ROS Production in Diabetic Cardiomyopathy

Figure 2

Hyperglycemia, hyperlipidemia, and myocardial ROS production. In diabetes, both the excess of plasma glucose (a) that cannot be properly assimilated by the tissues and the abundance of plasma lipids (b) may induce oxidative stress in the heart by different mediators. UCPs, uncoupling proteins.
461967.fig.002a
(a)
461967.fig.002b
(b)