How Histopathology Can Contribute to an Understanding of Defense Mechanisms against Cryptococci

<table>Analysis of the molecular function of stored genes was conducted using the Biological Networks Gene Ontology tool (BINGO, <a href="http://www.psb.ugent.be/cbd/papers/BiNGO">http://www.psb.ugent.be/cbd/papers/BiNGO/</a>) to identify statistically overrepresented GO categories among the biological data. For the 184 genes upregulated only in the lungs of mice infected with <i>C. gattii</i> TIMM 4097, 163 terms related to molecular functioning were detected, and GO terms related to binding accounted for about 75% of all terms.</table>

Mediators of Inflammation

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Figure 14

Figure 14: How Histopathology Can Contribute to an Understanding of Defense Mechanisms against Cryptococci 