Review Article

How Histopathology Can Contribute to an Understanding of Defense Mechanisms against Cryptococci

Figure 3

(a) An ultrastructural examination of the macrophage in mice infected with C. neoformans TIMM 0362 showed that a large number of phagocytized lipid droplets and a small number of the yeasts, as well as lesser developed organelles. (b) An ultrastructural examination of the macrophage in mice infected with C. neoformans TIMM 0372 showed a large number of developed organelles, including rough endoplasmic reticulum and Golgi.
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(a)
465319.fig.003b
(b)