Clinical Study
Association between Preoperative Plasma sRAGE Levels and Recovery from Cardiac Surgery
Table 1
The main clinical and biochemical characteristics, operative variables, and postoperative outcomes of study patientsa.
| | Preoperative characteristics | | Age, median (IQR) years | 71 (63–77) | | Male, (%) | 81 (62.3) | | Body mass index, median (IQR) kg/m2 | 25.7 (23.5–30.0) | | Creatinine μmol/L | 91 (77.5–107.5) | | EuroSCORE, median (IQR) | 7 (4–8) |
| | Operative variables | | Operation | | | CABG alone, (%) | 1 (0.8) | | Valve repair/replacement, (%) | 73 (56.2) | | CABG plus valve surgery, (%) | 56 (43.1) | | Cardiopulmonary bypass duration, median (IQR) min | 115.5 (92.0–141.0) | | Ischaemic time, median (IQR) min | 85.5 (67.0–108.0) |
| | Postoperative outcomes | | CRP postop day 1 versus preop, median (IQR) mg/L | 61 (46–94) versus 2 (1–5)† | | IL-8 2 h postop versus preop, median (IQR) pg/mL | 47.6 (29.5–83.0) versus 3.7 (0.0–8.3)‡ | | PaO2 : FiO2 ratio, mean (SEM), mmHg | 280.0 (8.3) | | Incidence of ALI | 0/130 | | Duration of ventilation, median (IQR) h | 16.3 (11.5–21.8) | | ICU length of stay, median (IQR) h | 40.5 (21.7–49.9) | | Level 3 care duration, median (IQR) h | 19.3 (13.7–40.8) | | Hospital length of stay, median (IQR) days | 8.9 (7.2–13.1) | | Hospital mortality, (%) | 5 (3.85) |
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IQR: interquartile range; SEM: standard error of the mean; ALI: acute lung injury; CABG: coronary artery bypass grafting; and ICU: intensive care unit.
patients undergoing cardiac surgery necessitating cardiopulmonary bypass.
, . , . Wilcoxon matched pairs test.
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