Table 1: The main clinical and biochemical characteristics, operative variables, and postoperative outcomes of study patientsa.

Preoperative characteristics
Age, median (IQR) years71 (63–77)
Male, (%)81 (62.3)
Body mass index, median (IQR) kg/m225.7 (23.5–30.0)
Creatinine μmol/L91 (77.5–107.5)
EuroSCORE, median (IQR)7 (4–8)

Operative variables
 CABG alone, (%)1 (0.8)
 Valve repair/replacement, (%)73 (56.2)
 CABG plus valve surgery, (%)56 (43.1)
Cardiopulmonary bypass duration, median (IQR) min115.5 (92.0–141.0)
Ischaemic time, median (IQR) min85.5 (67.0–108.0)

Postoperative outcomes
CRP postop day 1 versus preop, median (IQR) mg/L61 (46–94) versus 2 (1–5)
IL-8 2 h postop versus preop, median (IQR) pg/mL47.6 (29.5–83.0) versus 3.7 (0.0–8.3)
PaO2 : FiO2 ratio, mean (SEM), mmHg280.0 (8.3)
Incidence of ALI0/130
Duration of ventilation, median (IQR) h16.3 (11.5–21.8)
ICU length of stay, median (IQR) h40.5 (21.7–49.9)
Level 3 care duration, median (IQR) h19.3 (13.7–40.8)
Hospital length of stay, median (IQR) days8.9 (7.2–13.1)
Hospital mortality, (%)5 (3.85)

IQR: interquartile range; SEM: standard error of the mean; ALI: acute lung injury; CABG: coronary artery bypass grafting; and ICU: intensive care unit.
patients undergoing cardiac surgery necessitating cardiopulmonary bypass.
, . , . Wilcoxon matched pairs test.