Association between Preoperative Plasma sRAGE Levels and Recovery from Cardiac Surgery

Table 2

Binary logistic regression analysis of level 3 care with patient characteristics, operative variables,and postoperative outcomes^a.

	Level 3 care > median (19.25 h)		Univariate analysis Odds ratio (95% CI)	𝑃	Multivariate analysis Odds ratio (95% CI)	𝑃
	No mean	Yes mean
Age	67.6	70.3	1.0 (1.0-1.0)	0.165
Ischaemic time	83.8	95.5	1.0 (1.0-1.0)	𝟎.𝟎𝟑𝟒^a	1.01 (1.0-1.0)	0.887
CPB time	112.4	125.7	1.0 (1.0-1.0)	𝟎.𝟎𝟒𝟏^a	1.0 (1.0-1.0)	0.550
Log creatinine	1.96	1.98	5.9 (0.3–124)	0.249
Log BMI	1.42	1.42	1.1 (0.1–119)	0.9742
Log EuroSCORE	0.73	0.77	2.2 (0.5–10.9)	0.325
Log sRAGE preop	−0.33	−0.31	8.5 (2.2–32.5)	0.002 ^a	16.6 (1.8–155.4)	0.014 ^b
Log sRAGE postop	0.34	0.42	3.7 (1.0–14.5)	0.065	0.24 (0.0–2.7)	0.244
Log S100A8/9 preop	−0.04	0.13	1.5 (0.3–6.8)	0.617
Log S100A8/9 postop	0.20	0.29	11.7 (1.5–89.4)	0.018 ^a	5.7 (0.6–52.1)	0.120

CPB: cardiopulmonary bypass; BMI: body mass index; and 𝑛=124.
aSignificant relationship following univariate analysis.
bSignificant relationship following multivariate analysis.