IRAK1/4-Targeted Anti-Inflammatory Action of Caffeic Acid

Figure 1

Effect of CA on NO and PGE₂ production and viability in LPS-treated RAW264.7 cells. (a) The chemical structure of CA. ((b) and (c)) Levels of NO and PGE₂ were determined by the Griess assay and EIA, respectively, from supernatants of RAW264.7 cells that had been treated with CA (0 to 400 μM) in the presence or absence of LPS (1 μg/mL) for 24 h. (d) RAW264.7 cell viability was determined by MTT assay. ^∗𝑃<0.05 and ^∗∗𝑃<0.01, compared to the control.

(a)

(b)

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(d)