Persistent Inflammation in the CNS during Chronic EAE Despite Local Absence of IL-17 Production
Figure 3
Production of cytokines by peripheral lymphoid organs. C57BL/6 mice were submitted to EAE induction and cytokine production was assayed in acute and chronic EAE stages. IFN-γ (a and e), TNF-α (b and f), IL-17 (c and g), and IL-10 (d and h) levels were measured in spleen (a, b, c, and d) and lymph node cell (e, f, g, and h) cultures stimulated with MOG. Data were presented by mean ± SE of 6 mice and representative of two independent experiments. *.
