Urinary Eosinophil Protein X in Childhood Asthma: Relation with Changes in Disease Control and Eosinophilic Airway Inflammation

Table 3

Correlations between the changes from baseline in uEPX and changes in clinical markers of asthma control.

		𝑟	𝑃 value
Symptom-free days (%)	T1	−0.06	0.53
	T2	0.10	0.32
FEV1 (% pred)	T1	−0.24	0.01
	T2	−0.21	0.03
Sputum eosinophils (%)	T1	0.10	0.64
	T2	0.40	0.11

T0: at baseline; T1: after a treatment period of 1 year; T2: after a treatment period of 2 years. FEV₁: forced expiratory volume in 1 second. The individual changes from baseline of uEPX and % eos are expressed as ratios. For FEV₁ and symptom-free days, the changes are expressed as the absolute differences of the measured percentages. Numbers evaluable for the change from baseline of % eos at T1 and T2 are 23 and 17, respectively. Data shown are Spearman rank correlations.