Dysregulated Circulating Dendritic Cell Function in Ulcerative Colitis Is Partially Restored by Probiotic Strain Lactobacillus casei Shirota
Figure 2
UC-DC enhanced expression of skin-homing molecules on stimulated T cells. (a) CLA/β7 dot plots of dividing T cells, following stimulation by 3% control or UC-DC. Numbers over each dot plot represent proportion of dividing T cells expressing β7 only, β7 and CLA, CLA only, or either β7 or CLA. (b) Histograms of CLA expression by dividing T cells, following stimulation by 3% control or UC-DC. On the right, summary graph of all experiments (). (c) Histograms of CCR4 expression by dividing T cells, following stimulation by 3% control or UC-DC. On the right, summary graph of all experiments (). Paired -test was applied; value <0.05 was considered statistically significant (*). All representative histograms/dot plots are from a single experiment representative of 3 independent experiments performed with similar results. Filled histograms represent positive staining; empty histograms represent background staining.
