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Mediators of Inflammation
Volume 2013, Article ID 617145, 8 pages
http://dx.doi.org/10.1155/2013/617145
Research Article

IL-10 Treatment Is Associated with Prohibitin Expression in the Crohn’s Disease Intestinal Fibrosis Mouse Model

1Department of Gastroenterology, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China
2Department of General Surgery, Shanghai Sixth People’s Hospital Affiliated to Shanghai Jiao Tong University, Shanghai 200233, China

Received 23 December 2012; Revised 28 February 2013; Accepted 5 March 2013

Academic Editor: Eduardo López-Collazo

Copyright © 2013 C. Yuan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. J. Cosnes, “Crohn’s disease phenotype, prognosis, and long-term complications: what to expect?” Acta Gastro-Enterologica Belgica, vol. 71, pp. 303–307, 2008. View at Google Scholar
  2. S. Nikolaus and S. Schreiber, “Diagnostics of inflammatory bowel disease,” Gastroenterology, vol. 133, no. 5, pp. 1670–1689, 2007. View at Publisher · View at Google Scholar · View at Scopus
  3. M. Artal-Sanz, W. Y. Tsang, E. M. Willems et al., “The mitochondrial prohibitin complex is essential for embryonic viability and germline function in Caenorhabditis elegans,” Journal of Biological Chemistry, vol. 278, no. 41, pp. 32091–32099, 2003. View at Google Scholar · View at Scopus
  4. S. Rastogi, B. Joshi, G. Fusaro, and S. Chellappan, “Camptothecin induces nuclear export of prohibitin preferentially in transformed cells through a CRM-1-dependent mechanism,” Journal of Biological Chemistry, vol. 281, no. 5, pp. 2951–2959, 2006. View at Publisher · View at Google Scholar · View at Scopus
  5. V. Sánchez-Quiles, E. Santamaría, V. Segura, L. Sesma, J. Prieto, and F. J. Corrales, “Prohibitin deficiency blocks proliferation and induces apoptosis in human hepatoma cells: molecular mechanisms and functional implications,” Proteomics, vol. 10, no. 8, pp. 1609–1620, 2010. View at Publisher · View at Google Scholar · View at Scopus
  6. M. S. Altus, C. M. Wood, D. A. Stewart et al., “Regions of evolutionary conservation between the rat and human prohibitin-encoding genes,” Gene, vol. 158, no. 2, pp. 291–294, 1995. View at Publisher · View at Google Scholar · View at Scopus
  7. A. L. Theiss, R. D. Idell, S. Srinivasan et al., “Prohibitin protects against oxidative stress in intestinal epithelial cells,” FASEB Journal, vol. 21, no. 1, pp. 197–206, 2007. View at Publisher · View at Google Scholar · View at Scopus
  8. K. S. Ko, M. L. Tomasi, A. Iglesias-Ara et al., “Liver-specific deletion of prohibitin 1 results in spontaneous liver injury, fibrosis, and hepatocellular carcinoma in mice,” Hepatology, vol. 52, no. 6, pp. 2096–2108, 2010. View at Publisher · View at Google Scholar · View at Scopus
  9. T. B. Zhou, Y. H. Qin, Z. Y. Li, H. L. Xu, Y. J. Zhao, and F. Y. Lei, “All-trans retinoic acid treatment is associated with prohibitin expression in renal interstitial fibrosis rats,” International Journal of Molecular Sciences, vol. 13, pp. 2769–2782, 2012. View at Google Scholar
  10. G. Monteleone, M. Boirivant, F. Pallone, and T. T. MacDonald, “TGF-β1 and Smad7 in the regulation of IBD,” Mucosal Immunology, vol. 1, supplement 1, pp. S50–S53, 2008. View at Publisher · View at Google Scholar · View at Scopus
  11. F. Verrecchia, A. Mauviel, and D. Farge, “Transforming growth factor-β signaling through the Smad proteins: role in systemic sclerosis,” Autoimmunity Reviews, vol. 5, no. 8, pp. 563–569, 2006. View at Publisher · View at Google Scholar · View at Scopus
  12. A. M. Gressner and R. Weiskirchen, “Modern pathogenetic concepts of liver fibrosis suggest stellate cells and TGF-β as major players and therapeutic targets,” Journal of Cellular and Molecular Medicine, vol. 10, no. 1, pp. 76–99, 2006. View at Publisher · View at Google Scholar · View at Scopus
  13. R. Kalluri, “EMT: when epithelial cells decide to become mesenchymal-like cells,” Journal of Clinical Investigation, vol. 119, no. 6, pp. 1417–1419, 2009. View at Publisher · View at Google Scholar · View at Scopus
  14. A. F. Petit-Bertron, T. Pedron, U. Groß et al., “Adherence modifies the regulation of gene expression induced by interleukin-10,” Cytokine, vol. 29, no. 1, pp. 1–12, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. H. Tamaki, H. Nakamura, A. Nishio et al., “Human thioredoxin-1 ameliorates experimental murine colitis in association with suppressed macrophage inhibitory factor production,” Gastroenterology, vol. 131, no. 4, pp. 1110–1121, 2006. View at Publisher · View at Google Scholar · View at Scopus
  16. J. Song, “EMT or apoptosis: a decision for TGF-β,” Cell Research, vol. 17, no. 4, pp. 289–290, 2007. View at Publisher · View at Google Scholar · View at Scopus
  17. A. L. Theiss, H. Laroui, T. S. Obertone et al., “Nanoparticle-based therapeutic delivery of prohibitin to the colonic epithelial cells ameliorates acute murine colitis,” Inflammatory Bowel Diseases, vol. 17, no. 5, pp. 1163–1176, 2011. View at Publisher · View at Google Scholar · View at Scopus
  18. T. Sato, H. Saito, J. Swensen et al., “The human prohibitin gene located on chromosome 17q21 is mutated in sporadic breast cancer,” Cancer Research, vol. 52, no. 6, pp. 1643–1646, 1992. View at Google Scholar · View at Scopus
  19. S. Y. Hsieh, T. C. Shin, C. Y. Yeh, C. J. Lin, Y. Y. Chou, and Y. S. Lee, “Comparative proteomic studies on the pathogenesis of human ulcerative colitis,” Proteomics, vol. 6, no. 19, pp. 5322–5331, 2006. View at Publisher · View at Google Scholar · View at Scopus
  20. S. I. Sato, A. Murata, T. Orihara et al., “Marine natural product aurilide activates the opa1-mediated apoptosis by binding to prohibitin,” Chemistry and Biology, vol. 18, no. 1, pp. 131–139, 2011. View at Publisher · View at Google Scholar · View at Scopus
  21. K. H. Berger and M. P. Yaffe, “Prohibitin family members interact genetically with mitochondrial inheritance components in Saccharomyces cerevisiae,” Molecular and Cellular Biology, vol. 18, no. 7, pp. 4043–4052, 1998. View at Google Scholar · View at Scopus
  22. C. L. Chen, K. J. Chou, P. T. Lee et al., “Erythropoietin suppresses epithelial to mesenchymal transition and intercepts Smad signal transduction through a MEK-dependent mechanism in pig kidney (LLC-PK1) cell lines,” Experimental Cell Research, vol. 316, no. 7, pp. 1109–1118, 2010. View at Publisher · View at Google Scholar · View at Scopus
  23. J. P. Burke, R. W. G. Watson, J. J. Mulsow, N. G. Docherty, J. C. Coffey, and P. R. O'Connell, “Endoglin negatively regulates transforming growth factor β1-induced profibrotic responses in intestinal fibroblasts,” British Journal of Surgery, vol. 97, no. 6, pp. 892–901, 2010. View at Publisher · View at Google Scholar · View at Scopus
  24. Y. P. Rubtsov and A. Y. Rudensky, “TGF beta signalling in control of T-cell-mediated self-reactivity,” Nature Reviews Immunology, vol. 7, pp. 443–453, 2007. View at Google Scholar
  25. M. F. Walsh, D. R. Ampasala, J. Hatfield et al., “Transforming growth factor-β stimulates intestinal epithelial focal adhesion kinase synthesis via Smad- and p38-dependent mechanisms,” American Journal of Pathology, vol. 173, no. 2, pp. 385–399, 2008. View at Publisher · View at Google Scholar · View at Scopus
  26. J. W. Kaspar, S. K. Niture, and A. K. Jaiswal, “Nrf2:INrf2 (Keap1) signaling in oxidative stress,” Free Radical Biology and Medicine, vol. 47, no. 9, pp. 1304–1309, 2009. View at Publisher · View at Google Scholar · View at Scopus
  27. M. Kobayashi and M. Yamamoto, “Nrf2-Keap1 regulation of cellular defense mechanisms against electrophiles and reactive oxygen species,” Advances in Enzyme Regulation, vol. 46, no. 1, pp. 113–140, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. I. Lastres-Becker, T. Cartmell, and F. Molina-Holgado, “Endotoxin preconditioning protects neurones from in vitro ischemia: role of endogenous IL-1β and TNF-α,” Journal of Neuroimmunology, vol. 173, no. 1-2, pp. 108–116, 2006. View at Publisher · View at Google Scholar · View at Scopus
  29. B. Loos, R. Smith, and A. M. Engelbrecht, “Ischaemic preconditioning and TNF-α-mediated preconditioning is associated with a differential cPLA2 translocation pattern in early ischaemia,” Prostaglandins Leukotrienes and Essential Fatty Acids, vol. 78, no. 6, pp. 403–413, 2008. View at Publisher · View at Google Scholar · View at Scopus
  30. E. García-Prieto, A. González-López, S. Cabrera et al., “Resistance to bleomycin-induced lung fibrosis in MMP-8 deficient mice is mediated by interleukin-10,” PLoS One, vol. 5, no. 10, Article ID e13242, 2010. View at Publisher · View at Google Scholar