Etanercept Attenuates Traumatic Brain Injury in Rats by Reducing Brain TNF-α Contents and by Stimulating Newly Formed Neurogenesis
Figure 2
Etanercept attenuated TBI-induced increased brain contused volume and increased brain TNF-α contents. *The TBI rats treated with vehicle (TBI + V) (lined column; ) showed a significant increase in both brain contused volume and TNF-α contents () compared with the untreated sham-TBI group (white column) 7 days after TBI. +The TBI rats treated with etanercept (TBI + E) (crossed column; ) showed a significant decrease in both brain contused volume and brain TNF-α contents () compared with the (TBI + V) group (lined column; ). Top panels depict representative contused stainings for one sham TBI rat, one TBI + V rat, and one TBI + E rat.
