The Role of EGFR/PI3K/Akt/cyclinD1 Signaling Pathway in Acquired Middle Ear Cholesteatoma

Table 2

Cell proliferation of EACKs responding to EGF, AG1478, and wortmannin was detected by MTT assay (mean ± SD).

	36 h	48 h	72 h
	Survival rate (%)	Survival rate (%)	Survival rate (%)
Control	100.0	100.0	100.0
EGF	118.2±2.3	132.5±2.8	149.1±3.2
EGF + AG1478	107.8±3.7	108.7±4.3	115.1±2.6
EGF + wortmannin	110.4±2.8	113.1±3.2	118.6±5.2