Mediators of Inflammation / 2013 / Article / Tab 2

Clinical Study

Expression of Inflammation-Related Genes Is Altered in Gastric Tissue of Patients with Advanced Stages of NAFLD

Table 2

List of genes significantly upregulated in gastric tissues of patients with the following pathological conditions.

GenesFold change values FDR significance (B-H pass test)

Advanced liver inflammation (score ≥ 3)/mild or no liver inflammation (score < 3)

CCL42.320.037635Yes
CXCL22.820.031209Yes
CCR53.160.025748Yes
IFNA23.910.028306Yes
IL193.480.025748Yes
IL1F84.030.029948Yes
CXCL64.30.037635Yes
IL84.820.025748Yes

Advanced steatosis (score ≥ 3)/mild or no steatosis (score < 3)

IL8RB1.56 0.027891Yes
CXCL141.770.033865Yes
IL1F102.240.049141Yes

NASH/No NASH

CCR92.960.047583Yes
CCR33.440.047583Yes
IL1RN3.950.021559Yes
IL99.490.021363Yes
IL8RA15.040.040682Yes

Fibrosis presence/no fibrosis

CCL174.810.029Yes

Advanced liver inflammation (score ≥ 3) ( ), advanced steatosis (score ≥ 3) ( ), NASH ( ), fibrosis ( ). Comparison was performed for groups of patients without the condition listed. NASH: nonalcoholic steatohepatitis.