Metabolic Syndrome in Rheumatoid Arthritis

Table 1

Five current definitions of metabolic syndrome.

Required	NCEP ATP3 2005	IDF 2006; Waist = 94 cm (men); or = 80 cm (women)	EGIR 1999; Insulin resistance; or fasting hyperinsulinemia in top 25 percent	WHO 1999	AACE 2003; High risk of insulin resistance; or BMI = 25 kg/m^2; or waist = 102 cm (men) or = 88 cm (women)
				Insulin resistance in top 25 percent;
				glucose = 6.1 mmol/L (110 mg/dL);
				2-hour glucose = 7.8 mmol/L (140 mg/dL)
Number of abnormalities	3	2	2	2	2
Glucose	mmol/L (100 mg/dL)	5.6 mmol/L (100 mg/dL)	6.1–6.9 mmol/L (110–125 mg/dL)		6.1 mmol/L (110 mg/dL);
	or drug treatment for elevated blood glucose	or diagnosed diabetes			2-hour glucose 7.8 mmol/L (140 mg/dL)
HDL cholesterol	<1.0 mmol/L (40 mg/dL) (men);	<1.0 mmol/L (40 mg/dL) (men);	<1.0 mmol/L (40 mg/dL)	<0.9 mmol/L (35 mg/dL) (men); <1.0 mmol/L (40 mg/dL) (women)	<1.0 mmol/L (40 mg/dL) (men);
	<1.3 mmol/L (50 mg/dL) (women);	<1.3 mmol/L (50 mg/dL) (women);			<1.3 mmol/L (50 mg/dL) (women)
	or drug treatment for low HDL-C	or drug treatment for low HDL-C
Triglycerides	1.7 mmol/L (150 mg/dL)	1.7 mmol/L (150 mg/dL)	2.0 mmol/L (180 mg/dL)	1.7 mmol/L (150 mg/dL)	1.7 mmol/L (150 mg/dL)
	or drug treatment for elevated triglycerides	or drug treatment for high triglycerides	or drug treatment for dyslipidemia
Obesity	Waist = 102 cm (men)		Waist = 94 cm (men)	Waist/hip ratio > 0.9 (men)
	or = 88 cm (women)		or = 80 cm (women)	or >0.85 (women)
				or BMI = 30 kg/m^2
Hypertension	130/85 mmHg	130/85 mmHg	140/90 mmHg	140/90 mmHg	130/85 mmHg
	or drug treatment for hypertension	or drug treatment for hypertension	or drug treatment for hypertension

NCEP: National Cholesterol Education Program; IDF: International Diabetes Federation; EGIR: Group for the Study of Insulin Resistance; WHO: World Health Organization; AACE: American Association of Clinical Endocrinologists.
HDL-C: high-density lipoprotein cholesterol, LDL: low-density lipoprotein cholesterol, BMI: body mass index.