Long Pentraxin 3: Experimental and Clinical Relevance in Cardiovascular Diseases
Figure 1
Effects of PTX3 in cardiovascular diseases. PTX3 plasma levels rapidly increase during atherosclerosis and MI in humans and mice. PTX3 could then interact with FGF2 and/or P-selectin and exert cardiovascular protective activities. On the contrary, PTX3 deficiency leads to increased heart damage and inflammation after MI and atherosclerosis.