Evaluation of Adipokines: Apelin, Visfatin, and Resistin in Children with Atopic Dermatitis

Table 1

Demographic and clinical characteristics of children with atopic dermatitis and healthy children.

Characteristics	Children with AD; (𝑛=27)	Healthy children; (𝑛=46)
Age, years, mean ± SE	9.9±0.99	11.7±3.7
Sex, 𝑛	M: 10; F: 17	M: 19; F: 27
Duration of AD, years, mean ± SE	6.24±0.37	—
SCORAD, mean ± SE	47.67±67
Serum total IgE, IU/mL, mean ± SE	768.23±174.3^#	50.11±0.93
Eosinophils, % (𝑛, cells/𝜇L), mean ± SE	8.5±1.38^‡	2.21±0.4
	(488.4±80.61)^†	(155.05±13.42)
Positive SPT, 𝑛 (%)	100 (100)	0
Total SPT wheal size, mm, mean ± SE	22.9±2.43	—
BMI	18.1±1.44	18.76±0.56
BMI-SDS	0.83±0.41	0.18±0.26
CRP (mg/L)	2.68±1.9	1.01±0.2
TG (mmol/L)	1.09±0.13	0.97±0.04
TC (mmol/L)	4.34±0.015	3.99±0.03
LDL-C (mmol/L)	2.29±0.015	1.99±0.06
HDL-C (mmol/L)	1.86±0.01	1.5±0.02

BMI: body mass index; BMI-SDS: body mass index-standard deviation scores; CRP: C-reactive protein; FEV₁, HDL-C: high-density lipoprotein cholesterol; IgE: immunoglobulin E; IU: international unit; LDL-C: low-density lipoprotein cholesterol; SE: standard error; SPT: skin prick test; TC: total cholesterol; TG: triglyceride.
All 𝑃 values from Mann-Whitney’s 𝑈-test. ^‡𝑃<0.05, ^†𝑃<0.01, and ^#𝑃<0.0002.