Downregulation of CD4+LAP+ and CD4+CD25+ Regulatory T Cells in Acute Coronary Syndromes

Table 1

Clinical characteristics of patients.

Characteristics	Control; (𝑛=30)	SA; (𝑛=29)	NSTEACS; (𝑛=30)	STEAMI; (𝑛=27)
Age (years)	61.0±9.0	67.5±8.1	65.2±10.6	65.1±9.8
Sex (male/female)	17/13	17/12	21/9	23/4
Hypertension, 𝑛 (%)	16 (53.3)	20 (69.0)	19 (63.3)	12 (44.4)
Diabetes, 𝑛 (%)	4 (13.3)	6 (20.7)	7 (23.3)	3 (11.1)
Tobacco, 𝑛 (%)	5 (16.7)	10 (34.5)	5 (16.7)	7 (25.9)
TC (mmol/L)	3.95±0.93	4.03±0.58	4.24±1.13	4.55±0.82
TG (mmol/L)	1.44±0.73	1.61±0.71	1.98±1.48	1.42±1.08
LDL-C (mmol/L)	2.25±0.61	2.39±0.68	2.50±0.86	2.67±0.72
HDL-C (mmol/L)	1.26±0.37	1.09±0.28	1.31±0.75	1.04±0.41
GLU (mmol/L)	5.15±1.46	5.89±2.72	5.75±2.36	6.07±2.54
CRP (mg/L)	1.95±1.63	2.62±2.32	4.91±1.92^∗	5.93±2.01^∗
LVEF (%)	66.00±4.41	62.55±6.12	59.23±11.16	43.41±8.60^∗
LVEDD (mm)	46.33±3.53	47.41±3.74	49.87±5.18	54.04±4.24
Gensini score	0	26.66±21.77^∗	40.35±25.00^∗	58.81±29.64^∗
GRACE score	—	—	106.07±27.74	160.93±22.58
Medications, 𝑛 (%)
Aspirin	5 (16.7)	12 (41.4)	12 (40.0)	5 (18.5)
𝛽-Blockers	4 (13.3)	6 (20.7)	7 (23.3)	4 (14.8)
ACEI/ARB	5 (16.7)	9 (31.0)	8 (26.7)	5 (18.5)
CCB	10 (33.3)	12 (41.4)	13 (43.3)	7 (25.9)
Nitrates	3 (10.0)	10 (34.5)	8 (26.7)	5 (18.5)
Statins	2 (6.7)	7 (24.1)	6 (20.0)	3 (11.1)

The data are given as the mean ± SD or number of patients. SA: stable angina; NSTEACS: non-ST-elevation acute coronary syndrome; STEAMI: ST-elevation acute myocardial infarction; TC: total cholesterol; TG: total triglycerides; LDL-C: low-density lipoprotein cholesterol; HDL-C: high-density lipoprotein cholesterol; GLU: fasting glucose; CRP: C-reactive protein; LVEF: left ventricular ejection fraction; LVEDD: left ventricular end-diastolic dimension; ACEI: angiotensin-converting enzyme inhibitor; ARB: angiotensin receptor blocker; CCB: calcium channel blocker.
^∗𝑃<0.05 versus control.