A Possible Role for CD8+ T Lymphocytes in the Cell-Mediated Pathogenesis of Pemphigus Vulgaris
Figure 1
(a) Histology of a PV lesion from a wild-type mice injected with PV IgG. (b) Direct immunofluorescence in wild-type mice injected with PV IgG showing IgG bounded to the intercellular cell surface (100x). (c) Histology of mice treated with IgG deprived plasma, no acantholysis is observed. Immunofluorescence studies were also negative (data not shown). (d) A large erosion on the back of a mice treated with PV IgG.
