Clinical Study
Immunoexpression of Interleukin-22 and Interleukin-23 in Oral and Cutaneous Lichen Planus Lesions: A Preliminary Study
Table 2
Expression of IL-22 and IL-23 in normal oral mucosa and skin and lichen planus (LP) samples*.
| | | Normal control | General LP | | Normal mucosa | Oral LP (OLP) | | Normal skin | Cutaneous LP (CLP) | | OLP versus CLP |
| | Variable | | | P value | | | P value | | | P value | P value | | IL-22 | | | | | | | | | | | | Epithelial | 3.58 (1.22) | 107.04 (20.43) | <0.001 | 5.67 (2.19) | 145.45 (36.38) | 0.024 | 1.70 (0.98) | 64.58 (12.74) | <0.001 | 0.918 | | Subepithelial | 1.26 (0.87) | 147.46 (23.70) | <0.001 | 0.89 (0.61) | 208.93 (40.35) | <0.001 | 1.60 (1.60) | 79.53 (17.12) | <0.001 | 0.036 | | IL-23 | | | | | | | | | | | | Epithelial | 2.68 (1.12) | 189.08 (28.14) | <0.001 | 3.11 (2.12) | 288.24 (46.57) | <0.001 | 2.30 (1.07) | 79.47 (16.89) | <0.001 | 0.003 | | Subepithelial | 1.21 (0.85) | 250.12 (32.97) | <0.001 | 2.56 (1.74) | 354.31 (53.82) | <0.001 | 0.00 (0.00) | 134.97 (25.58) | <0.001 | 0.006 |
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*Values are expressed as the number of positive cells, mean (standard error mean).
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