Mediators of Inflammation / 2013 / Article / Tab 2

Clinical Study

Inflammation, Haemostatic Disturbance, and Obesity: Possible Link to Pathogenesis of Diabetic Retinopathy in Type 2 Diabetes

Table 2

Basic characteristics, inflammatory and haemostatic markers, other markers of endothelial dysfunction, and anthropometric and clinical parameters of type 2 diabetic patients ( ) divided into three groups according to the diabetic retinopathy status.

DR group 1
( )
DR group 2
( )
DR group 3
( )
Chi-squarec

Age (years)*66.31 ± 8.3168.47 ± 7.1166.52 ± 7.980.543a0.583a
Sex (m/f)**65/3542/5874/260.28c0.595c
Diabetes duration (years)*13.22 ± 5.0816.11 ± 6.0119.35 ± 4.6012.498a
Therapy (OHA/insulin)**48/5232/6813/877.52c
C-reactive protein (CRP) (mg/L)*3.37 ± 4.144.05 ± 3.345.36 ± 5.771.721a0.184a
Fibrinogen (g/L)*4.73 ± 1.234.75 ± 1.484.75 ± 1.090.002a0.998a
HbA1c (%)*6.42 ± 1.066.53 ± 1.066.70 ± 1.290.551a0.578a
(%)*6.77 ± 0.767.18 ± 0.817.31 ± 0.852.976a0.055a
Total cholesterol (mmol/L)*4.96 ± 0.854.87 ± 1.275.05 ± 1.050.178a0.838a
Triglycerides (mmol/L)*2.14 ± 1.192.48 ± 2.411.50 ± 0.611.230a0.066a
Body mass index (BMI) (kg/m²)*30.77 ± 6.0630.91 ± 5.2830.12 ± 5.330.129a 0.879a
Waist circumference (WC) (cm)*107.52 ± 14.96108.21 ± 12.09107.91 ± 12.280.020a 0.980a
Waist-to-hip ratio (WHR)*0.96 ± 0.080.96 ± 0.070.97 ± 0.070.162a0.851a
Systolic blood pressure (mmHg)*139.00 ± 22.97151.32 ± 23.85144.35 ± 21.182.267a 0.109a
Diastolic blood pressure (mmHg)*82.15 ± 12.9080.26 ± 15.5078.70 ± 8.150.691a0.503a

mean ± SD, percentage, aANOVA df = 2, cChi-square test df = 1.
OHA: oral hypoglycemic agent; HbA1c: glycated hemoglobin value determined at the beginning of the study from a single venous blood sample; : glycated hemoglobin value obtained by statistical analysis of data from the National Registry for Diabetes (CroDiabNet).

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