Contribution of CFTR to Alveolar Fluid Clearance by Lipoxin A4 via PI3K/Akt Pathway in LPS-Induced Acute Lung Injury
Figure 2
Effects of lipoxin A4 on AFC in LPS-induced ALI. Lipoxin A4 (2 μg/kg) was administered intravenously to Sprague-Dawley (SD) rats 6 h after LPS (20 mL/kg) stimulation through the tail vein, and intratracheal instillation of 5% albumin solution containing Evans Blue-labeled albumin through a tracheostomy to the left lung, ventilating for 1 hour. was instilled with albumin solution. Data were expressed as mean ± SEM for each group. * versus control group, # versus LPS group, for each group. LPS = lipopolysaccharide, LXA4 = lipoxin A4.
