Contribution of CFTR to Alveolar Fluid Clearance by Lipoxin A4 via PI3K/Akt Pathway in LPS-Induced Acute Lung Injury
Figure 4
Effects of lipoxin A4 on protein expression of CFTR in primary ATII cells. The cells were treated with lipoxin A4 (100 nM) in the presence of LPS (1 μg/mL) for 6 hours. (a) After incubation, the cells were harvested, sonicated and CFTR protein detected by western blotting. (b) The protein expression of CFTR also was detected by immunofluorescence assay. Data were expressed as mean ± SEM for each group. * versus control group, # versus LPS group, for each group. LPS = lipopolysaccharide, LXA4 = lipoxin A4, CFTR = cystic fibrosis transmembrane conductance regulator.
