High-Mobility Group Box-1 Induces Decreased Brain-Derived Neurotrophic Factor-Mediated Neuroprotection in the Diabetic Retina

Table 2

Pearson correlation coefficients between serum levels of the studied factors.

	BNDF	HMGB1	MCP-1	TBARS	sICAM-1
HMGB1	𝑟=−0.324
	𝑃=0.049^∗
MCP-1	𝑟=0.089	−0.156
	𝑃=0.519	0.250
TBARS	𝑟=−0.115	0.121	0.344
	𝑃=0.413	0.382	0.012^∗
sICAM	𝑟=−0.103	−0.016	0.168	0.303
	𝑃=0.450	0.907	0.219	0.032^∗
sRAGE	𝑟=−0.253	0.252	0.241	0.335	0.431
	𝑃=0.070	0.068	0.085	0.018^∗	<0.001*

∗Statistically significant at 5% level of significance.
Where the row and column meet is the correlation coefficient and the 𝑃 value for the two variables.
BDNF: brain-derived neurotrophic factor; HMGB1: high-mobility group box-1; MCP-1: monocyte chemoattractant protein-1; TBARS: thiobarbituric acid reactive substance; sICAM-1: soluble intercellular adhesion molecule-1; sRAGE: soluble receptor for advanced glycation end products.