The Effects of Proresolution of Ellagic Acid in an Experimental Model of Allergic Airway Inflammation
Figure 1
Ellagic acid prevents the development of airway inflammatory responses in experimental airways allergic inflammation. Mice received ellagic acid (10 mg/kg, p.o.), dexamethasone (1 mg/kg, s.c.), or vehicle (water, p.o.) 30 minutes prior in accordance to the preventive protocol (see Section 2) and euthanized on 21 or 25 days and cells in bronchoalveolar lavage were counted (a). BALF cells and leukocytes subset at 21 days (b); BALF cells and leukocytes subset at 25 days (c). One group of animals received vehicle (control group). Results represent the mean ± SEM, of two or more independent experiments with four mice per group per experiment. compared with control group; compared with ovalbumin + vehicle group.
