E. coli Endotoxin Modulates the Expression of Sirtuin Proteins in PBMC in Humans

Figure 1

SIRT1, SIRT2, and SIRT mRNA expressions in PBMC following LPS administration. (a) SIRT1 mRNA was decreased 3 hours after LPS challenge (RQ 0.58; 𝑃<0.01). (b) SIRT2 mRNA was not altered within 24 hours after LPS. (c) SIRT3 mRNA was decreased 6 hours after LPS challenge (RQ 0.49; 𝑃<0.01). Results are mean±SD (𝑛=7).

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(b)

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