Regulation of Immune Cell Infiltration into the CNS by Regional Neural Inputs Explained by the Gate Theory

<table>Venules at the blood-brain barrier in the CNS and other organs. Venules at the blood-brain barrier consist of specific endothelial cells that are brought together by tight junctions and tight liner sheets formed by pericytes and astrocytic end-feet. These are not present in normal venules (left).</table>

Mediators of Inflammation

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Figure 1

Figure 1: Regulation of Immune Cell Infiltration into the CNS by Regional Neural Inputs Explained by the Gate Theory 