Research Article

Azithromycin Prevents Pregnancy Loss: Reducing the Level of Tumor Necrosis Factor-Alpha and Raising the Level of Interleukin-10 in Rats

Table 2

TNFα and IL-10 levels of groups.

TNFα (pg/mL)IL-10 (pg/mL)

ControlND90.2 ± 4.31a
Azithromycin58.2 ± 9.56a113 ± 15.4a
LPS 128 ± 10.7b496 ± 149b
Azithromycin + LPS96.6 ± 10.2c1130 ± 87.4c

TNFα: tumor necrosis factor α; IL-10: interleukin-10; LPS: lipopolysaccharide (160 µg kg−1 intravenously, Escherichia coli 0111:B4). ND: not determined. a,b,cDifferent letters in the same column are statistically significant ( ).