Research Article

Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection

Figure 7

Celecoxib treatment increases the survival of mice infected with lethal inoculum of H. capsulatum. Mice infected with a lethal inoculum of H. capsulatum (1 × 106 yeast) were treated daily p.o. with water or celecoxib (1 mg/kg/0.5 mL) for 30 days . A group of noninfected mice were used as controls . #Hc + H2O versus Hc + celecoxib. , using logrank test.
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