5-Lipoxygenase-Dependent Recruitment of Neutrophils and Macrophages by Eotaxin-Stimulated Murine Eosinophils
Accumulation of different leukocyte types induced by eotaxin: effect of MK886. BALB/c mice were pretreated with vehicle (methylcellulose) or MK886 and injected with RPMI medium (negative control, open bars) or eotaxin, 50 ng/cavity (black bars). Peritoneal lavage fluid collected after 4 h was used for quantitation of total leukocytes (a), eosinophils (b), macrophages (c), and neutrophils (d). Data are mean ± SEM. *, ; **, , for the differences relative to the respective negative control in each group. Data from 6 experiments.