Research Article

Diethylcarbamazine Attenuates the Development of Carrageenan-Induced Lung Injury in Mice

Figure 5

Effect of DEC on immunohistochemical localization TNF-α in lung after carrageenan-induced pleurisy. (a) In tissue sections obtained from the CAR group, positive staining for TNF-α was mainly located in inflammatory cells. (b) After treatment with DEC, the degree of positive staining for TNF-α was reduced in the lung tissue. (c) Densitometry analysis of immunohistochemistry photographs for TNF-α in lung tissues; figure representative of at least 3 experiments performed on different experimental days; data expressed as mean ± S.E.M. from mice for each group; ND: not detected; versus carrageenan; scale bar = 20 μm.
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