Diethylcarbamazine Attenuates the Development of Carrageenan-Induced Lung Injury in Mice

Figure 6

Effects of DEC on immunohistochemical localization of IL-1β. (a) At 4 h after carrageenan injection, staining intensity for IL-1β substantially increased in alveolar macrophages. (b) No positive staining for IL-1 was found when DEC was administered three days prior to carrageenan injection. (c) Densitometry analysis of immunohistochemistry photographs for IL-1-β in lung tissues; figure representative of at least 3 experiments performed on different experimental days; data expressed as mean ± S.E.M. from 𝑛=5 mice for each group; ND: not detected; ^∗𝑃<0.05 versus carrageenan; scale bar = 20 μm.

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