The Beta-2-Adrenoreceptor Agonists, Formoterol and Indacaterol, but Not Salbutamol, Effectively Suppress the Reactivity of Human Neutrophils In Vitro
Figure 6
Fura-2 fluorescence traces from 2 representative experiments ( –7 in the series) showing the effects of formoterol, indacaterol, and salbutamol (10 and 100 nM) on the alterations in cytosolic Ca2+ concentrations following activation of the cells with either 1 μM fMLP (a) or 200 nM PAF (b). The 3 lines in each trace correspond to the control system (—) and systems treated with either 10 nM (_ _) or 100 nM (●●●●●) of each drug; denotes the addition of either fMLP or PAF.
