Research Article

A Novel Rose Hip Preparation with Enhanced Anti-Inflammatory and Chondroprotective Effects

Figure 1

Effect of RH on production of PGE2 and cytokines by activated peripheral blood leukocytes.
(a) Total PBLs were stimulated with LPS/IFN-γ for 24 h without or with graded amounts of RH preparations. Secreted analytes were determined as detailed in Materials and Methods. Symbols on the y-axis indicate the amount of analytes detected on LPS/IFN-γ only stimulated cells. Straight line: RH-A; dashed line: RH-B. , (LPS/IFN-γ only versus LPS/IFN-γ+RH)
(b) Production of PGE2, various chemokines, and interleukins by unstimulated PBL. Note the logarithmic scale on the y-axis. RH-A and RH-B were tested at 500 μg/mL. and indicate the statistically significant differences between RH-A and RH-B