Mediators of Inflammation / 2014 / Article / Tab 2

Research Article

Diagnostic Utility of Broad Range Bacterial 16S rRNA Gene PCR with Degradation of Human and Free Bacterial DNA in Bloodstream Infection Is More Sensitive Than an In-House Developed PCR without Degradation of Human and Free Bacterial DNA

Table 2

Patients with positive BC, ST, or IHP. Bacterial infection was considered confirmed when plausible pathogens were found in blood culture and by molecular methods.

CaseComorbiditiesConventional microbiologySTIHPBacterial infection

1Acute cholecystitisKlebsiella pneumoniae (blood culture and respiratory tract)Klebsiella pneumoniae Klebsiella pneumonia Confirmed

2Alcoholic liver cirrhosisStaphylococcus aureus (blood culture)Staphylococcus aureus NegativeConfirmed

3Knee prosthesisStaphylococcus aureus (blood culture and knee joint aspirate)Staphylococcus aureus NegativeConfirmed

4Congestive heart failure, generalized atherosclerosisNegativeStreptococcus pneumoniae Streptococcus pneumoniae Plausible pathogen

5Congestive heart failure, diabetes type IINegativeStreptococcus pneumoniae Streptococcus pneumoniae Plausible pathogen

6Diabetes type II, chronic obstructive pulmonary diseaseNegativeStreptococcus pneumoniae NegativePlausible pathogen

7Injection drug use, endocarditisNegativeStreptococcus salivarius NegativePlausible pathogen

8Chronic renal failure, diabetes mellitusNegativeStaphylococcus hominis NegativeConsidered contamination

9Colon cancerNegativeStreptococcus mitis group NegativeConsidered contamination

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