Mediators of Inflammation / 2014 / Article / Tab 1

Review Article

Interleukin-17 Gene Polymorphisms Contribute to Cancer Risk

Table 1

Characteristics of case-control studies on IL-17A rs2275913G>A and IL-17F rs763780 T>C polymorphisms and cancer risk included in the meta-analysis.

First authorYearCountryEthnicitySource of controlsCaseControlGenotype distributionP for HWEa MAF Genotyping method Cancer category
CaseControl
G/GG/AA/AG/GG/AA/A

Zhang [20] 2014ChinaAsianPopulation controls2605121101024825818767<0.010.31MassARRAYGastric cancer
Zhou [21] 2013ChinaAsianHospital controls3014467915468164204780.290.40TaqManBladder cancer
Zhu [22] 2014ChinaAsianHospital controls29355012612245273216610.070.31MassARRAYGastric cancer
Rafiei [23]2013IranCaucasianHealthy controls1611715661447872210.490.33PCR-RFLPGastric cancer
Quan [24]2012ChinaAsianHospital controls3114639314276168215800.430.40TaqManCervical cancer
Arisawa [25]2012JapanAsianHospital controls33358311213784218293720.080.37PCR-SSCPGastric cancer
Wang [26]2012ChinaAsianPopulation controls49150116523492198245580.170.36SNaPshot SNP assayBreast cancer
Wu [27]2010ChinaAsianPopulation controls9457682104852501933712040.350.51PCR-RFLPGastric cancer
Chen [28] 2010ChinaAsianPopulation controls104210903005222203255412240.970.45TaqManGastric cancer
Shibata [15]2009JapanAsianHospital controls287523941246917529949<0.010.38PCR-SSCPGastric cancer

T/TT/CC/CT/TT/CC/C

Zhang [20]2014ChinaAsianPopulation controls26051220930214295330<0.010.11MassARRAYGastric cancer
Zhou [21]2013ChinaAsianHospital controls30144624057431712450.060.15TaqManBladder cancer
Zhu [22]2014ChinaAsianHospital controls29355024135174635829<0.010.11MassARRAYGastric cancer
Quan [24]2012ChinaAsianHospital controls31146222285433212650.060.15TaqManCervical cancer
Wang [26]2012ChinaAsianPopulation controls49150238210363969970.770.11SNaPshot SNP assayBreast cancer
Wu [27]2010ChinaAsianPopulation controls92777754033255527214360.020.18PCR-RFLPGastric cancer
Shibata [15]2009JapanAsianHospital controls28052322155441910040.460.10PCR-SSCPGastric cancer

HWE in control.
MAF: minor allele frequency in control group.