(i) Exhibited the inhibition of hydroxyl radical-mediated degradation by iron ion chelation .
(ii) Exhibited the inhibition of linoleic acid oxidation, protected human LDL from oxidative modification, and protected against plasmid DNA strand breakage induced by peroxyl free radicals .
(iii) Exhibited against hydroxyl and peroxyl radicals in in vitro assays .
(iv) Inhibited activities of NF-B and AP-1 induced by G/GO .
(v) Reduced intracellular ROS formation caused by H2O2, reduced TBARS formation, and attenuated catalase depletion at concentration of 100 /mL .
(vi) Prevented cisplatin-induced ROS release against MDCK-I cells .
(vii) Protected human keratinocytes against oxidative stress caused by H2O2 .
Exhibited antiviral activity against fish pathogenic IHNV and VHSV .
(i) Protected the murine hippocampal HT22 cells against glutamate-induced neurotoxicity .
(ii) Protected dopaminergic neuronal cells in a rotenone model of PD .
(iii) Protected against 6-OHDA-induced neuronal cell death of PD .
(iv) Protected against rotenone-induced toxicity by preventing the downregulation of BDNF and GDNF in human dopaminergic cells, SH-SY5Y [35, 36].
(i) Inhibited platelet aggregation via inhibition of receptor expression on platelet membranes, including glycoprotein IIb/IIIa (CD41), GPIIb/IIIa-like expression (PAC-1), and P-selectin (CD62), and intracellular calcium mobilization responses and decreased platelet activation were observed for the isomaltol- and pentagalloyl glucose-treated platelets .
(ii) Exhibited anti-AKR1B10 activity at 1 M with an IC50 value of 1.47 M .
(iii) Suppressed IL-4 and -10 in BPA-stimulated primary cultured mouse lymphocytes .