The Inhibitory Effect of PIK-75 on Inflammatory Mediator Response Induced by Hydrogen Peroxide in Feline Esophageal Epithelial Cells

Figure 8

Effect of PIK-75 on IL-6 release in feline EECs stimulated by H₂O₂. Serum-starved EECs were preincubated in the presence of PIK-75. EECs were then stimulated with H₂O₂ (300 μM, 6 hours). The production of IL-6 was measured in supernatants by ELISA. Data are expressed as means ± S.E of four experiments (Student’s t-test; versus control, versus H₂O₂ alone).