The Effect of a Community-Based, Primary Health Care Exercise Program on Inflammatory Biomarkers and Hormone Levels

Table 2

Inflammatory biomarkers and hormone concentration levels (mean, standard deviation) at baseline, after 6 months, and after 1 year of exercise intervention.

Biomarker	BL	6 M	1 Y	𝑃 value; BL versus 6 M	𝑃 value; BL versus 1 Y	𝑃 value; 6 M versus 1 Y
CRP (mg·L^−1)	3.4±1.2	3.0±1.2	1.5±1.0^∗𝛼	0.999	0.001	0.003
IL10 (pg·mL^−1)	4.8±2.0	4.4±2.3	4.2±1.5	0.988	0.681	0.602
IL6 (pg·mL^−1)	4.4±1.1	4.2±1.5	3.4±0.7	0.999	0.236	0.163
TNFα (pg·mL^−1)	10.6±5.6	7.6±4.0	5.6±3.0^∗𝛼	0.082	0.001	0.004
Leptin (ng/mL^−1)	2.69±2.25	2.30±1.66	7.60±4.89^∗𝛼	0.999	0.016	0.003
Insulin (ng/mL^−1)	1.09±1.01	0.83±0.41	0.67±0.17	0.898	0.405	0.642
IL10/TNF𝛼	0.59±0.4	0.64±0.2	0.85±0.3	—	—	—

BL: baseline; 6 M: 6 months; 1 Y: 1 year; CRP: C-reactive protein; IL10: interleukin 10; IL6: interleukin 6; TNF𝛼: tumor necrosis factor alpha.
*Statistically significant difference from baseline.
𝛼Statistically significant difference after 6 months.