An Overview of the Role of Innate Lymphoid Cells in Gut Infections and Inflammation

Table 1

Markers expressed by various subsets of innate lymphoid cells (ILCs).

ILC group	ILC lineage	Marker
1	ILC1	LIN−, CD25 low, CD56−, IL-7R𝛼+, CD161+/−, NKp44−, NKp46−, IL-1R+, ICOS+, IL-12R𝛽2+, and CRTH2−
	NK cells	LIN−, CD56+, CD25+/−, IL-7R𝛼+/−, CD161+/−, NKp44+/−, NKp46+, IL-12R𝛽2+, and CRTH2−
2	ILC2	LIN−, CD25 low, CD117+/−, IL-7R𝛼+, ICOS+, IL-1R+, ST2+, IL-17RB+, CRTH2+, and CD161+
3	ILC3	LIN−, CD25 low, CD117+, IL-7R𝛼+, CD161+, NKp44+, NKp46+, CRTH−, IL-1R+, IL-23+, and ICOS+
	LTi cells	LIN−, CD117+, IL-7R𝛼+, CD161+/−, IL-1R+, and IL-23+

LIN, lineage; NK, natural killer; LTi, lymphoid tissue-inducer; IL, interleukin; CRTH2, chemoattractant receptor homologous molecule; ICOS, inducible T cell costimulator; R, receptor; ST2, subunit of IL-33R.