Research Article

The Protective Effects of the Supercritical-Carbon Dioxide Fluid Extract of Chrysanthemum indicum against Lipopolysaccharide-Induced Acute Lung Injury in Mice via Modulating Toll-Like Receptor 4 Signaling Pathway

Table 2

The effects of CFE on LPS-induced the levels of MDA, SOD, CAT, and GPx.

GroupsMDA (nmol/mg protein)SOD (U/mg protein) CAT (U/mg protein) GPx (U/mg protein)

Sham0.29 ± 0.02 1.03 ± 0.080.67 ± 0.050.32 ± 0.04
LPS1.18 ± 0.10#0.31 ± 0.02#0.11 ± 0.03#0.10 ± 0.03#
Dex (5 mg/kg)0.62 ± 0.06**0.57 ± 0.06**0.39 ± 0.06**0.17 ± 0.03**
CFE (120 mg/kg)0.49 ± 0.06**0.62 ± 0.05**0.42 ± 0.03**0.20 ± 0.02**
CFE (80 mg/kg)0.53 ± 0.04**0.53 ± 0.05**0.38 ± 0.05**0.17 ± 0.05**
CFE (40 mg/kg)0.56 ± 0.06**0.44 ± 0.05**0.36 ± 0.06**0.16 ± 0.02**

Data represented the mean ± SEM ( = 10). compared to the sham group; and compared to LPS group.