The Protective Effects of the Supercritical-Carbon Dioxide Fluid Extract of Chrysanthemum indicum against Lipopolysaccharide-Induced Acute Lung Injury in Mice via Modulating Toll-Like Receptor 4 Signaling Pathway
Table 3
The effects of CFE on LPS-induced the levels of TNF-α, IL-1β, and IL-6.
Groups
TNF-α (pg/mg protein)
IL-1β (ng/mg protein)
IL-6 (ng/mg protein)
Sham
31.97 ± 2.47
2.36 ± 0.22
5.52 ± 0.74
LPS
123.7 ± 4 9.36#
13. 41 ± 1.13#
20.20 ± 2.47#
Dex (5 mg/kg)
79.81 ± 13.56**
5.28 ± 0.61**
9.66 ± 1.57**
CFE (120 mg/kg)
69.49 ± 9.71**
5. 67 ± 0.83**
10.80 ± 1.69**
CFE (80 mg/kg)
77.43 ± 11.29**
6.08 ± 0.52**
11.96 ± 1.21**
CFE (40 mg/kg)
93.49 ± 6.50*
7. 92 ± 1.24*
12.33 ± 1.09**
Data represented the mean ± SEM ( = 10). compared to the sham group; and compared to LPS group.
