Mediators of Inflammation / 2014 / Article / Tab 2

Research Article

Effect of Th17 and Treg Axis Disorder on Outcomes of Pulmonary Arterial Hypertension in Connective Tissue Diseases

Table 2

Concentrations of serum cytokines and NT-proBNP determined by radioimmunoassay or Elecsys NT-proBNP sandwich immunoassay (pg/mL).

VariableControl ()CTD ()CTD-aPAH
Total () Mild to moderate ()Severe ()

IL-17a 56.54 ± 13.9565.47 ± 19.77*74.68 ± 25.28*#66.50 ± 21.40
IL-6 86.05 ± 35.83*97.26 ± 39.34*88.00 ± 38.40103.84 ± 39.28
IFN-1002.62 ± 273.61*1083.08 ± 275.64*1131.68 ± 264.09
IL-2 686.48 ± 183.92*719.53 ± 241.91*
TNF-329.65 ± 102.05*361.34 ± 118.41*
TGF-93.91 ± 21.50*71.17 ± 18.95*#
NT-pro BNP 215.94 ± 78.20*453.04 ± 149.50*#

*Compared with control group, ; #compared with CTD group, ; §compared with mild to moderate CTD-aPAH group, .