Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient

<table><i>Immunoreactivity for 4-HNE in AKU aortic valve leaflet. </i>The presence of 4-HNE in the AKU valve was uniformly diffused and the distribution of 4-HNE-positive area was perfectly superimposing to ochronotic pigmented areas. The presence of lipid peroxidation and ochronotic pigment was found to be strictly related to areas of lymphocytes accumulation. Magnification 20x.</table>

Mediators of Inflammation

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Figure 7

Figure 7: Amyloidosis, Inflammation, and Oxidative Stress in the Heart of an Alkaptonuric Patient 